TrumpRx’s 85% Price Cut Stuns Healthcare World

Open pill bottle with white tablets spilled out.

President Trump’s revolutionary TrumpRx platform promises to slash prescription drug prices by up to 85%, delivering on his campaign promise to finally break Big Pharma’s stranglehold on American families.

Story Highlights

  • TrumpRx.gov launches as federal direct-to-consumer platform offering drugs at international pricing levels
  • Popular diabetes and obesity medications like Ozempic and Wegovy drop from $1,350 to $350 monthly through Most-Favored-Nation deals
  • Trump uses 100% tariff threats to force pharmaceutical companies into pricing agreements and domestic manufacturing commitments
  • Platform bypasses insurance middlemen and pharmacy benefit managers that have inflated costs for decades

Trump Delivers on Drug Pricing Promise

President Trump announced TrumpRx on September 30, 2025, as a federal direct-to-consumer platform designed to eliminate the corrupt pricing schemes that have plagued American healthcare. The initiative represents the most aggressive federal intervention against pharmaceutical price gouging in decades, forcing drug manufacturers to offer Americans the same low prices enjoyed by other developed nations through Most-Favored-Nation pricing agreements.

Massive Price Cuts Target High-Cost Medications

The White House announced dramatic price reductions for popular GLP-1 diabetes and obesity medications beginning November 6, 2025. Ozempic prices will plummet from approximately $1,000 monthly to $350, while Wegovy drops from $1,350 to the same $350 rate. Zepbound and other leading treatments face similar cuts, with projections showing prices could fall to $245 monthly within two years as competition intensifies.

These reductions represent genuine relief for millions of Americans who have been forced to ration medications or go without treatment entirely due to astronomical costs. The platform promises average discounts of 50% across participating medications, with some treatments marked down by 85% compared to current U.S. list prices through partnerships with transparent pricing advocates like Mark Cuban’s Cost Plus Drugs.

Tariff Strategy Forces Industry Compliance

Trump’s approach combines diplomatic pressure with economic leverage, threatening 100% tariffs on imported branded drugs unless manufacturers agree to Most-Favored-Nation pricing and commit to expanding U.S. manufacturing operations. This strategy has already secured five major deals with pharmaceutical giants including Pfizer, Eli Lilly, and Novo Nordisk, demonstrating that firm negotiation tactics can succeed where previous administrations failed.

The administration’s full operational launch is targeted for early 2026, with additional manufacturer partnerships expected as companies recognize the benefits of avoiding punitive tariffs while accessing expanded market opportunities through transparent pricing models.

Sources:

TrumpRx and MFN Pricing – Truveris

Trump Administration Prescription Drug Initiatives: What Employers Should Know – Aon

A Pivotal Week in Pharmaceutical Policy for the Trump Administration – Mintz

Drug Pricing in the Era of Trump 2.0 – Georgetown University

Fact Sheet: President Donald J. Trump Announces Major Developments in Bringing Most-Favored-Nation Pricing to American Patients – White House

Fact Sheet: President Donald J. Trump Announces Second Deal to Bring Most-Favored-Nation Pricing to American Patients – White House

Understanding the Trump Administration’s Negotiated Drug Prices for Medicare – KFF